activity
20122022
most citedThe ancient Operational Code is embedded in the amino acid substitution matrix and aaRS phylogenies

18 citations · 23 across the 6 of their papers we have counts for

collaborators

8 papers

q-bio.PE2022

Evaluation of the relative performance of the subflattenings method for phylogenetic inference

Joshua Stevenson, Barbara Holland, Michael Charleston +1

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern…

q-bio.PE2021

The Shape of Phylogenies Under Phase-Type Distributed Times to Speciation and Extinction

Albert Ch. Soewongsono, Barbara R. Holland, Małgorzata M. O'Reilly

Phylogenetic trees are widely used to understand the evolutionary history of organisms. Tree shapes provide information about macroevolutionary processes. However, macroevolutionar…

q-bio.PE201918 cited

The ancient Operational Code is embedded in the amino acid substitution matrix and aaRS phylogenies

Julia A. Shore, Barbara R. Holland, Jeremy G. Sumner +2

The underlying structure of the canonical amino acid substitution matrix (aaSM) is examined by considering stepwise improvements in the differential recognition of amino acids acco…

q-bio.PE2018

The impracticalities of multiplicatively-closed codon models: a retreat to linear alternatives

Julia A. Shore, Jeremy G. Sumner, Barbara R. Holland

A matrix Lie algebra is a linear space of matrices closed under the operation . The "Lie closure" of a set of matrices is the smallest matrix Lie algebra which co…

q-bio.PE20175 cited

Exploring the consequences of lack of closure in codon models

Michael D. Woodhams, Jeremy G. Sumner, David A. Liberles +2

Models of codon evolution are commonly used to identify positive selection. Positive selection is typically a heterogeneous process, i.e., it acts on some branches of the evolution…

q-bio.PE2017

Distinguishing between convergent evolution and violation of the molecular clock

Jonathan D. Mitchell, Jeremy G. Sumner, Barbara R. Holland

We give a non-technical introduction to convergence-divergence models, a new modeling approach for phylogenetic data that allows for the usual divergence of species post speciation…