10 papers
A Principle-Driven Adaptive Policy for Group Cognitive Stimulation Dialogue for Elderly with Cognitive Impairment
Jiyue Jiang, Yanyu Chen, Pengan Chen +7
Cognitive impairment is becoming a major public health challenge. Cognitive Stimulation Therapy (CST) is an effective intervention for cognitive impairment, but traditional methods…
Large Language Models in Bioinformatics: A Survey
Zhenyu Wang, Zikang Wang, Jiyue Jiang +3
Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of…
Investigating Data Pruning for Pretraining Biological Foundation Models at Scale
Yifan Wu, Jiyue Jiang, Xichen Ye +9
Biological foundation models (BioFMs), pretrained on large-scale biological sequences, have recently shown strong potential in providing meaningful representations for diverse down…
TreeSynth: Synthesizing Diverse Data from Scratch via Tree-Guided Subspace Partitioning
Sheng Wang, Pengan Chen, Jingqi Zhou +7
Model customization necessitates high-quality and diverse datasets, but acquiring such data remains time-consuming and labor-intensive. Despite the great potential of large languag…
DS-ProGen: A Dual-Structure Deep Language Model for Functional Protein Design
Yanting Li, Jiyue Jiang, Zikang Wang +11
Inverse Protein Folding (IPF) is a critical subtask in the field of protein design, aiming to engineer amino acid sequences capable of folding correctly into a specified three-dime…
Biological Sequence with Language Model Prompting: A Survey
Jiyue Jiang, Zikang Wang, Yuheng Shan +5
Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models s…