4 papers
An Agnostic Biosignature Based on Modeling Panspermia and Terraforming
Harrison B. Smith, Lana Sinapayen
The search for a second instance of life is one of the greatest problems of modern science. Outside of creating an artificial origin of life on Earth, the primary targets for the s…
Historical Contingencies Steer the Topology of Randomly Assembled Graphs
Cole Mathis, Harrison B. Smith
Graphs are used to represent and analyze data in domains as diverse as physics, biology, chemistry, planetary science, and the social sciences. Across domains, random graph models…
Challenge-Based Funding to Spark Origins Breakthroughs
Cole Mathis, Harrison B. Smith
Origins of life research is marred by ambiguous questions and goals, creating uncertainty about when research objectives have been achieved. Because of numerous unknowns and disagr…
Single-cell metabolic flux analysis reveals coexisting optimal sub-groups, cross-feeding, and mixotrophy in a cyanobacterial population
Arián Ferrero-Fernández, Paula Prondzinsky, Lucia Gastoldi +5
We derive a single-cell level understanding of metabolism in an isogenic cyanobacterial population by integrating secondary ion mass spectrometry (SIMS) derived multi-isotope uptak…