224 citations · 1.4k across the 48 of their papers we have counts for
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Nuclear mechanics controls the temporal dynamics of cell unjamming
Leon Hillmann, Quirine J. S. Braat, Pablo Gottheil +9
Cell unjamming in dense tissues is a complex but essential process in embryogenesis and cancer metastasis. Increasing evidence suggests that nuclear mechanics and density effects p…
Shape matters: Inferring the motility of confluent cells from static images
Quirine J. S. Braat, Giulia Janzen, Bas C. Jansen +3
Cell motility in dense cell collectives is pivotal in various diseases like cancer metastasis and asthma. A central aspect in these phenomena is the heterogeneity in cell motility,…
Formation of motile cell clusters in heterogeneous model tumors: the role of cell-cell alignment
Quirine J. S. Braat, Cornelis Storm, Liesbeth M. C. Janssen
Circulating tumor cell clusters play an important role in the metastatic cascade. These clusters can acquire a migratory and more invasive phenotype, and coordinate their motion to…
Enhanced persistence and collective migration in cooperatively aligning cell clusters
Vincent E. Debets, Liesbeth M. C. Janssen, Cornelis Storm
Most cells possess the capacity to locomote. Alone or collectively, this allows them to adapt, to rearrange, and to explore their surroundings. The biophysical characterization of…