25 citations · 87 across the 19 of their papers we have counts for
7 papers · 1 filter
PDXpower: A Power Analysis Tool for Experimental Design in Pre-clinical Xenograft Studies for Uncensored and Censored Outcomes
Shanpeng Li, Donatello Telesca, Harley I. Kornblum +5
In cancer research, leveraging patient-derived xenografts (PDXs) in pre-clinical experiments is a crucial approach for assessing innovative therapeutic strategies. Addressing the i…
Region-Referenced Spectral Power Dynamics of EEG Signals: A Hierarchical Modeling Approach
Qian Li, John Shamshoian, Damla Senturk +4
Functional brain imaging through electroencephalography (EEG) relies upon the analysis and interpretation of high-dimensional, spatially organized time series. We propose to repres…
Inferring Brain Signals Synchronicity from a Sample of EEG Readings
Qian Li, Damla Senturk, Catherine A. Sugar +4
Inferring patterns of synchronous brain activity from a heterogeneous sample of electroencephalograms (EEG) is scientifically and methodologically challenging. While it is intuitiv…
A Bayesian regression tree approach to identify the effect of nanoparticles' properties on toxicity profiles
Cecile Low-Kam, Donatello Telesca, Zhaoxia Ji +4
We introduce a Bayesian multiple regression tree model to characterize relationships between physico-chemical properties of nanoparticles and their in-vitro toxicity over multiple…
Comparison of Clustering Methods for Time Course Genomic Data: Applications to Aging Effects
Yafeng Zhang, Steve Horvath, Roel Ophoff +1
Time course microarray data provide insight about dynamic biological processes. While several clustering methods have been proposed for the analysis of these data structures, compa…
Toxicity profiling of engineered nanomaterials via multivariate dose-response surface modeling
Trina Patel, Donatello Telesca, Saji George +1
New generation in vitro high-throughput screening (HTS) assays for the assessment of engineered nanomaterials provide an opportunity to learn how these particles interact at the ce…