88 citations · 258 across the 13 of their papers we have counts for
4 papers · 1 filter
Edge effects in game theoretic dynamics of spatially structured tumours
Artem Kaznatcheev, Jacob G. Scott, David Basanta
Background: Analysing tumour architecture for metastatic potential usually focuses on phenotypic differences due to cellular morphology or specific genetic mutations, but often ign…
Mathematical modeling of the metastatic process
Jacob G. Scott, Philip Gerlee, David Basanta +3
Mathematical modeling in cancer has been growing in popularity and impact since its inception in 1932. The first theoretical mathematical modeling in cancer research was focused on…
A Markov chain model of evolution in asexually reproducing populations: insight and analytical tractability in the evolutionary process
Daniel Nichol, Peter Jeavons, Robert Bonomo +5
The evolutionary process has been modelled in many ways using both stochastic and deterministic models. We develop an algebraic model of evolution in a population of asexually repr…
Intrinsic cell factors that influence tumourigenicity in cancer stem cells - towards hallmarks of cancer stem cells
Jacob G. Scott, Prakash Chinnaiyan, Alexander R. A. Anderson +2
Since the discovery of a cancer initiating side population in solid tumours, studies focussing on the role of so-called cancer stem cells in cancer initiation and progression have…