88 citations · 258 across the 13 of their papers we have counts for
3 papers · 1 filter
Mathematical modeling of the metastatic process
Jacob G. Scott, Philip Gerlee, David Basanta +3
Mathematical modeling in cancer has been growing in popularity and impact since its inception in 1932. The first theoretical mathematical modeling in cancer research was focused on…
Intrinsic cell factors that influence tumourigenicity in cancer stem cells - towards hallmarks of cancer stem cells
Jacob G. Scott, Prakash Chinnaiyan, Alexander R. A. Anderson +2
Since the discovery of a cancer initiating side population in solid tumours, studies focussing on the role of so-called cancer stem cells in cancer initiation and progression have…
A mathematical model of tumor self-seeding reveals secondary metastatic deposits as drivers of primary tumor growth
Jacob G Scott, David Basanta, Alexander R. A. Anderson +1
Two models of circulating tumor cell (CTC) dynamics have been proposed to explain the phenomenon of tumor 'self-seeding', whereby CTCs repopulate the primary tumor and accelerate g…