88 citations · 231 across the 8 of their papers we have counts for
5 papers · 1 filter
Limited Resources Induce Bistability in Microtubule Length Regulation
Matthias Rank, Aniruddha Mitra, Louis Reese +2
The availability of protein is an important factor for the determination of the size of the mitotic spindle. Involved in spindle-size regulation is kinesin-8, a molecular motor and…
A nonequilibrium diffusion and capture mechanism ensures tip-localization of regulating proteins on dynamic filaments
Emanuel Reithmann, Louis Reese, Erwin Frey
Diffusive motion of regulatory enzymes on biopolymers with eventual capture at a reaction site is a common feature in cell biology. Using a lattice gas model we study the impact of…
Quantifying protein diffusion and capture on filaments
Emanuel Reithmann, Louis Reese, Erwin Frey
The functional relevance of regulating proteins is often limited to specific binding sites such as the ends of microtubules or actin-filaments. A localization of proteins on these…
Cooperative effects enhance the transport properties of molecular spider teams
Matthias Rank, Louis Reese, Erwin Frey
Molecular spiders are synthetic molecular motors based on DNA nanotechnology. While natural molecular motors have evolved towards very high efficiency, it remains a major challenge…
Crowding of molecular motors determines microtubule depolymerization
Louis Reese, Anna Melbinger, Erwin Frey
Assembly and disassembly dynamics of microtubules (MTs) is tightly controlled by MT associated proteins. Here, we investigate how plus-end-directed depolymerases of the kinesin-8 f…