2 papers
physics.bio-ph2026
In vitro binding energies capture Klf4 occupancy across the human genome
Anne Schwager, Jonas Neipel, Yahor Savich +4
Transcription factors (TFs) regulate gene expression by binding to specific genomic loci determined by DNA sequence. Their sequence specificity is commonly summarized by a consensu…
physics.bio-ph2025
Active Loop Extrusion guides DNA-Protein Condensation
Ryota Takaki, Yahor Savich, Jan Brugués +1
The spatial organization of DNA involves DNA loop extrusion and the formation of protein-DNA condensates. While the significance of each process is increasingly recognized, their i…