2 papers
stat.ME2026
Proximal Learning for Trials With External Controls: A Case Study in HIV Prevention
Yilin Song, Yinxiang Wu, Raphael J. Landovitz +9
With the advent of effective pre-exposure prophylaxis agents, active-controlled HIV prevention trials have become a common study design. Nevertheless, estimating absolute efficacy…
stat.ME2025
A General Framework for Designing and Evaluating Active-Controlled Trials with Non-Inferiority Objectives
Antonio Olivas-Martinez, Fei Gao, Holly Janes
Active-controlled trials with non-inferiority objectives are often used when effective interventions are available, but new options may offer advantages or meet public health needs…