3 papers
stat.ME2026
Proximal Learning for Trials With External Controls: A Case Study in HIV Prevention
Yilin Song, Yinxiang Wu, Raphael J. Landovitz +9
With the advent of effective pre-exposure prophylaxis agents, active-controlled HIV prevention trials have become a common study design. Nevertheless, estimating absolute efficacy…
stat.ME2025
Group Identification and Variable Selection in Multivariable Mendelian Randomization with Highly-Correlated Exposures
Yinxiang Wu, Neil M. Davies, Ting Ye
Multivariable Mendelian Randomization (MVMR) estimates the direct causal effects of multiple risk factors on an outcome using genetic variants as instruments. The growing availabil…
stat.ME2025
A More Robust Approach to Multivariable Mendelian Randomization
Yinxiang Wu, Hyunseung Kang, Ting Ye
Multivariable Mendelian randomization (MVMR) uses genetic variants as instrumental variables to infer the direct effects of multiple exposures on an outcome. However, unlike univar…