activity
20112026
most citedA multiphase Cahn-Hilliard-Darcy model for tumour growth with necrosis

87 citations · 466 across the 33 of their papers we have counts for

collaborators

39 papers

math.AP2026

Permeability parameter asymptotics in a Cahn--Hilliard system with third type transmission conditions

Pierluigi Colli, Takeshi Fukao, Kei Fong Lam

In this paper, we study a system in which the Cahn--Hilliard system is imposed in the bulk domain and an Allen--Cahn type equation is prescribed on the boundary, connected through…

math.AP2026

On a Mullins-Sekerka model for the growth of active droplets modelling protocells: Stability analysis and numerical computations

Harald Garcke, Kei Fong Lam, Robert Nürnberg +1

Mullins-Sekerka models with chemical reactions can lead to scenarios where droplets grow, become unstable, split, grow and undergo further division. These grow and division cycles…

math.AP2025★ 1 cited

On a Cahn-Hilliard equation for the growth and division of chemically active droplets modeling protocells

Harald Garcke, Kei Fong Lam, Robert Nürnberg +1

The Cahn-Hilliard model with reaction terms can lead to situations in which no coarsening is taking place and, in contrast, growth and division of droplets occur which all do not g…

math.NA2025★ 4 cited

Stability and convergence of relaxed scalar auxiliary variable schemes for Cahn-Hilliard systems with bounded mass source

Kei Fong Lam, Ru Wang

The scalar auxiliary variable (SAV) approach of Shen et al. (2018), which presents a novel way to discretize a large class of gradient flows, has been extended and improved by many…

math.NA2024

Numerical analysis of a FE/SAV scheme for a Caginalp phase field model with mechanical effects in stereolithography

Xingguang Jin, Kei Fong Lam, Changqing Ye

In this work we propose a phase field model based on a Caginalp system with mechanical effects to study the underlying physical and chemical processes behind stereolithography, whi…

math.OC2022★ 9 cited

Phase field topology optimisation for 4D printing

Harald Garcke, Kei Fong Lam, Robert Nürnberg +1

This work concerns a structural topology optimisation problem for 4D printing based on the phase field approach. The concept of 4D printing as a targeted evolution of 3D printed st…

math.OC2021

Overhang penalization in additive manufacturing via phase field structural topology optimization with anisotropic energies

Harald Garcke, Kei Fong Lam, Robert Nürnberg +1

A phase field approach for structural topology optimization with application to additive manufacturing is analyzed. The main novelty is the penalization of overhangs (regions of th…

math.OC2020★ 24 cited

Sparse optimal control of a phase field tumour model with mechanical effects

Harald Garcke, Kei Fong Lam, Andrea Signori

In this paper, we study an optimal control problem for a macroscopic mechanical tumour model based on the phase field approach. The model couples a Cahn--Hilliard type equation to…

math.AP2020

On the Existence of Strong Solutions to the Cahn-Hilliard-Darcy system with mass source

Andrea Giorgini, Kei Fong Lam, Elisabetta Rocca +1

We study a diffuse interface model describing the evolution of the flow of a binary fluid in a Hele-Shaw cell. The model consists of a Cahn-Hilliard-Darcy (CHD) type system with tr…

math.AP2020★ 2 cited

Strong well-posedness and inverse identification problem of a non-local phase field tumor model with degenerate mobilities

S. Frigeri, K. F. Lam, A. Signori

We extend previous weak well-posedness results obtained in Frigeri et al. (2017) concerning a non-local variant of a diffuse interface tumor model proposed by Hawkins-Daarud et al.…

math.AP2020★ 62 cited

Phase-field dynamics with transfer of materials: The Cahn--Hilliard equation with reaction rate dependent dynamic boundary conditions

Patrik Knopf, Kei Fong Lam, Chun Liu +1

The Cahn--Hilliard equation is one of the most common models to describe phase separation processes of a mixture of two materials. For a better description of short-range interacti…

math.AP2019★ 50 cited

On a phase field model of Cahn-Hilliard type for tumour growth with mechanical effects

Harald Garcke, Kei Fong Lam, Andrea Signori

Mechanical effects have mostly been neglected so far in phase field tumour models that are based on a Cahn-Hilliard approach. In this paper we study a macroscopic mechanical model…

math.AP2019

Weak and stationary solutions to a Cahn-Hilliard-Brinkman model with singular potentials and source terms

Matthias Ebenbeck, Kei Fong Lam

We study a phase field model proposed recently in the context of tumour growth. The model couples a Cahn-Hilliard-Brinkman (CHB) system with a elliptic reaction-diffusion equation…

math.AP2019★ 31 cited

Convergence of a Robin boundary approximation for a Cahn--Hilliard system with dynamic boundary conditions

Patrik Knopf, Kei Fong Lam

We prove the existence of unique weak solutions to an extension of a Cahn--Hilliard model proposed recently by C.~Liu and H.~Wu (2019), in which the new dynamic boundary condition…

math.AP2019

Sharp interface limit of a non-mass-conserving Cahn--Hilliard system with source terms and non-solenoidal Darcy flow

Kei Fong Lam

We study the sharp interface limit of a non-mass-conserving Cahn--Hilliard--Darcy system with the weak compactness method developed in Chen (J. Differential Geometry, 1996). The so…

math.AP2019★ 5 cited

Convergence to equilibrium for a bulk--surface Allen--Cahn system coupled through a Robin boundary condition

Kei Fong Lam, Hao Wu

We consider a coupled bulk--surface Allen--Cahn system affixed with a Robin-type boundary condition between the bulk and surface variables. This system can also be viewed as a rela…

math.NA2018

Phase field modelling of surfactants in multi-phase flow

Oliver R. A. Dunbar, Kei Fong Lam, Bjorn Stinner

A diffuse interface model for surfactants in multi-phase flow with three or more fluids is derived. A system of Cahn-Hilliard equations is coupled with a Navier-Stokes system and a…

math.NA2018★ 23 cited

Bayesian parameter identification in Cahn-Hilliard models for biological growth

Christian Kahle, Kei Fong Lam, Jonas Latz +1

We consider the inverse problem of parameter estimation in a diffuse interface model for tumour growth. The model consists of a fourth-order Cahn-Hilliard system and contains three…

math.AP2018★ 17 cited

On a coupled bulk-surface Allen-Cahn system with an affine linear transmission condition and its approximation by a Robin boundary condition

Pierluigi Colli, Takeshi Fukao, Kei Fong Lam

We study a coupled bulk-surface Allen-Cahn system with an affine linear transmission condition, that is, the trace values of the bulk variable and the values of the surface variabl…

math.AP2018

Cahn--Hilliard inpainting with the double obstacle potential

Harald Garcke, Kei Fong Lam, Vanessa Styles

The inpainting of damaged images has a wide range of applications, and many different mathematical methods have been proposed to solve this problem. Inpainting with the help of Cah…

math.AP2017

On a multi-species Cahn-Hilliard-Darcy tumor growth model with singular potentials

Sergio Frigeri, Kei Fong Lam, Elisabetta Rocca +1

We consider a model describing the evolution of a tumor inside a host tissue in terms of the parameters , (proliferating and dead cells, respectively), (cell velocit…

math.OC2017

Parameter identification via optimal control for a Cahn--Hilliard-chemotaxis system with a variable mobility

Christian Kahle, Kei Fong Lam

We consider the inverse problem of identifying parameters in a variant of the diffuse interface model for tumour growth model proposed by Garcke, Lam, Sitka and Styles (Math. Model…

math.AP2017★ 12 cited

On a diffuse interface model for tumour growth with non-local interactions and degenerate mobilities

Sergio Frigeri, Kei Fong Lam, Elisabetta Rocca

We study a non-local variant of a diffuse interface model proposed by Hawkins--Darrud et al. (2012) for tumour growth in the presence of a chemical species acting as nutrient. The…

math.AP2017★ 38 cited

Thermodynamically Consistent Navier--Stokes--Cahn--Hilliard Models with Mass Transfer and Chemotaxis

Kei Fong Lam, Hao Wu

We derive a class of Navier--Stokes--Cahn--Hilliard systems that models two-phase flows with mass transfer coupled to the process of chemotaxis. These thermodynamically consistent…