17 citations · 18 across the 5 of their papers we have counts for
4 papers · 1 filter
Study of the Parent-of-origin effect in monogenic diseases with variable age of onset. Application on ATTRv
Flora Alarcon, Violaine Planté-Bordeneuve, Gregory Nuel
In genetic diseases with variable age of onset, an accurate estimation of the survival function for the mutation carriers and also modifying factors effects estimations are importa…
Computing Individual Risks based on Family History in Genetic Disease in the Presence of Competing Risks
G Nuel, Antoine Lefebvre, O Bouaziz
When considering a genetic disease with variable age at onset (ex: diabetes , familial amyloid neuropathy, cancers, etc.), computing the individual risk of the disease based on fam…
From GWAS to transcriptomics in prospective cancer design - new statistical challenges
Sandra Plancade, Gregory Nuel, Eiliv Lund
Background. With the increasing interest in post-GWAS research which represents a transition from genome-wide association discovery to analysis of functional mechanisms, attention…
Hidden Markov Model Applications in Change-Point Analysis
The Minh Luong, Vittorio Perduca, Gregory Nuel
The detection of change-points in heterogeneous sequences is a statistical challenge with many applications in fields such as finance, signal analysis and biology. A wide variety o…