1.1k citations · 1.2k across the 6 of their papers we have counts for
7 papers
Generating eukaryotic reference genome assemblies: Earth BioGenome Project quality standards and recommendations
Kerstin Howe, Dolores R. Agius, Tyler Alioto +45
Reference genome assemblies are foundational resources across the biological sciences as they begin to expose the fundamental building blocks of each species and the molecular tool…
Evaluation of tools for differential gene expression analysis by RNA-seq on a 48 biological replicate experiment
Nicholas J. Schurch, Pieta Schofield, Marek Gierliński +9
An RNA-seq experiment with 48 biological replicates in each of 2 conditions was performed to determine the number of biological replicates () required, and to identify the mos…
Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment
Marek Gierliński, Christian Cole, Pietà Schofield +9
High-throughput RNA sequencing (RNA-seq) is now the standard method to determine differential gene expression. Identifying differentially expressed genes crucially depends on estim…
The evolution of tyrosine-recombinase elements in Nematoda
Amir Szitenberg, Georgios Koutsovoulos, Mark L Blaxter +1
Transposable elements can be categorised into DNA and RNA elements based on their mechanism of transposition. Tyrosine recombinase elements (YREs) are relatively rare and poorly un…
Palaeosymbiosis revealed by genomic fossils of Wolbachia in a strongyloidean nematode
Georgios Koutsovoulos, Benjamin Makepeace, Vincent N. Tanya +1
Wolbachia are common endosymbionts of terrestrial arthropods, and are also found in nematodes: the animal-parasitic filaria, and the plant-parasite Radopholus similis. Lateral tran…
The complex hybrid origins of the root knot nematodes revealed through comparative genomics
David H Lunt, Sujai Kumar, Georgios Koutsovoulos +1
Meloidogyne root knot nematodes (RKN) can infect most of the world's agricultural crop species and are among the most important of all plant pathogens. As yet however we have littl…
Major changes in the core developmental pathways of nematodes: Romanomermis culicivorax reveals the derived status of the Caenorhabditis elegans model
Philipp H. Schiffer, Michael Kroiher, Christopher Kraus +13
Background Despite its status as a model organism, the development of Caenorhabditis elegans is not necessarily archetypical for nematodes. The phylum Nematoda is divided into the…