1.5k citations · 4.4k across the 76 of their papers we have counts for
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"Water to the ropes": a predictive model for the supercontraction stress of spider silks
Vincenzo Fazio, Nicola Maria Pugno, Giuseppe Puglisi
When humidified at different moisture conditions, restrained spider silk fibers can exhibit a very high supercontraction phenomenon. The hydration water molecules induce a Hydrogen…
Cooperative melting in double-stranded peptide chains through local mechanical interactions
Luca Bellino, Giuseppe Florio, Alain Goriely +1
Under an external field a double-stranded peptide chain can separate in a fragile or ductile transition. It is usually believed that these two regimes are driven either by chemical…
Growth of a flexible fibre in a deformable ring
Arsenio Cutolo, Massimiliano Fraldi, Gaetano Napoli +1
We study the equilibrium configurations related to the growth of an elastic fibre in a confining flexible ring. This system represents a paradigm for a variety of biological, medic…
A predictive microstructure-based approach for the anisotropic damage, residual stretches and hysteresis in biodegradable sutures
Gennaro Vitucci, Domenico De Tommasi, Giuseppe Puglisi +1
We propose a predictive model for the mechanical behavior of biodegradable polymers of interest for biomedical applications. Starting from a detailed description of the network beh…
Spider silks mechanics: predicting humidity and temperature effects
Giuseppe Puglisi, Domenico De Tommasi, Vincenzo Fazio +1
We deduce a microstructure inspired model for humidity and temperature effects on the mechanical response of spider silks, modelled as a composite material with a hard crystalline…
On the influence of device handle in single-molecule experiments
L. Bellino, G. Florio, G. Puglisi
We deduce a fully analytical model to predict the artifacts of the measuring device handles in Single Molecule Force Spectroscopy experiments. As we show, neglecting the effects of…
Unveiling the influence of device stiffness in single macromolecule unfolding
G. Florio, G Puglisi
Single-molecule stretching experiments on DNA, RNA, and other biological macromolecules opened up the possibility of an impressive progress in many fields of Life and Medical scien…
Catastrophic thinning of dielectric elastomers
Giuseppe Zurlo, Michel Destrade, Domenico DeTommasi +1
We provide a clear energetic insight into the catastrophic nature of the so-called creasing and pull-in instabilities in soft electro-active elastomers. These phenomena are ubiquit…
Multiscale mechanics of macromolecular materials with unfolding domains
Domenico De Tommasi, Giuseppe Puglisi, Giuseppe Saccomandi
We propose a general multiscale approach for the mechanical behavior of three-dimensional networks of macromolecules undergoing strain-induced unfolding. Starting from a (statistic…
An energetic model for macromolecules unraveling
Domenico De Tommasi, Nicola Millardi, Giuseppe Puglisi +1
We propose a simple approach, based on the minimization of the total (entropic plus unfolding) energy of a two-state system, describing the stretch-induced unfolding of macromolecu…