6 papers
From Phase Grounding to Intelligent Surgical Narratives
Ethan Peterson, Huixin Zhan
Video surgery timelines are an important part of tool-assisted surgeries, as they allow surgeons to quickly focus on key parts of the procedure. Current methods involve the surgeon…
Biosecurity-Aware AI: Agentic Risk Auditing of Soft Prompt Attacks on ESM-Based Variant Predictors
Huixin Zhan
Genomic Foundation Models (GFMs), such as Evolutionary Scale Modeling (ESM), have demonstrated remarkable success in variant effect prediction. However, their security and robustne…
SafeGenes: Evaluating the Adversarial Robustness of Genomic Foundation Models
Huixin Zhan, Clovis Barbour, Jason H. Moore
Genomic Foundation Models (GFMs), such as Evolutionary Scale Modeling (ESM), have demonstrated significant success in variant effect prediction. However, their adversarial robustne…
Agentic Surgical AI: Surgeon Style Fingerprinting and Privacy Risk Quantification via Discrete Diffusion in a Vision-Language-Action Framework
Huixin Zhan, Jason H. Moore
Surgeons exhibit distinct operating styles shaped by training, experience, and motor behavior-yet most surgical AI systems overlook this personalization signal. We propose a novel…
Long-range gene expression prediction with token alignment of large language model
Edouardo Honig, Huixin Zhan, Ying Nian Wu +1
Gene expression is a cellular process that plays a fundamental role in human phenotypical variations and diseases. Despite advances of deep learning models for gene expression pred…
DYNA: Disease-Specific Language Model for Variant Pathogenicity
Huixin Zhan, Zijun Zhang
Clinical variant classification of pathogenic versus benign genetic variants remains a challenge in clinical genetics. Recently, the proposition of genomic foundation models has im…