2 papers
q-bio.QM2013
Detecting the structure of haplotypes, local ancestry and excessive local European ancestry in Mexicans
Yongtao Guan
We present a two-layer hidden Markov model to detect structure of haplotypes for unrelated individuals. This allows modeling two scales of linkage disequilibrium (one within a grou…
stat.ME2012
Small World MCMC with Tempering: Ergodicity and Spectral Gap
Yongtao Guan, Matthew Stephens
When sampling a multi-modal distribution , $x\in \rr^d$, a Markov chain with local proposals is often slowly mixing; while a Small-World sampler \citep{guankrone} -- a Markov…