4 papers
Shape-Independent Fluidity in Epithelial Cell Monolayers
Pradip K. Bera, Anh Q. Nguyen, Molly McCord +2
Tissue fluidity regulates biological processes such as embryonic development, wound healing, and cancer metastasis. In confluent epithelia, where cell packing fraction is effective…
Measurement of tissue viscosity to relate force and motion in collective cell migration
Molly McCord, Jacob Notbohm
In tissue development, wound healing, and cancer invasion, coordinated cell motion arises from active forces produced by the cells. The relationship between force and motion remain…
Energy injection in an epithelial cell monolayer indicated by negative viscosity
Molly McCord, Jacob Notbohm
Epithelial tissues are driven out of thermodynamic equilibrium by internally generated forces, causing complex patterns of motion. Even when both the forces and motion are measurab…
Traction and Stress Control Formation and Motion of +1/2 Topological Defects in Epithelial Cell Monolayers
Pradip K. Bera, Molly McCord, Jun Zhang +1
In confluent cell monolayers, patterns of cell forces and motion are systematically altered near topological defects in cell shape. In turn, defects have been proposed to alter cel…