3 papers
cs.CE2026
TrinityDNA: A Bio-Inspired Foundational Model for Efficient Long-Sequence DNA Modeling
Qirong Yang, Yucheng Guo, Zicheng Liu +7
The modeling of genomic sequences presents unique challenges due to their length and structural complexity. Traditional sequence models struggle to capture long-range dependencies…
cs.LG2025
Life-Code: Central Dogma Modeling with Multi-Omics Sequence Unification
Zicheng Liu, Siyuan Li, Zhiyuan Chen +6
The interactions between DNA, RNA, and proteins are fundamental to biological processes, as illustrated by the central dogma of molecular biology. Although modern biological pre-tr…
q-bio.GN2025
EnTao-GPM: DNA Foundation Model for Predicting the Germline Pathogenic Mutations
Zekai Lin, Haoran Sun, Yucheng Guo +8
Distinguishing pathogenic mutations from benign polymorphisms remains a critical challenge in precision medicine. EnTao-GPM, developed by Fudan University and BioMap, addresses thi…