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stat.ME2026
Living forwards or understanding backwards? A comparison of Inverse Probability of Treatment Weighting and G-estimation methods for targeting hypothetical full adherence estimands in longitudinal cohort studies
Xiaoran Liang, Deniz Türkmen, Jane A H Masoli +2
Medication adherence is essential to ensure treatment effectiveness, but too often in routine care non-adherence compromises the desired outcome. We explore longitudinal causal mod…
stat.ME2024
Instrumental Variable methods to target Hypothetical Estimands with longitudinal repeated measures data: Application to the STEP 1 trial
Jack Bowden, Jesper Madsen, Bryan Goldman +3
The STEP 1 randomized trial evaluated the effect of taking semaglutide vs placebo on body weight over a 68 week duration. As with any study evaluating an intervention delivered ove…