3 papers
physics.optics2026
Differentiable Microscopy Designs an All Optical Phase Retrieval Microscope
Kithmini Herath, Hasindu Kariyawasam, Ramith Hettiarachchi +7
Designing new optical systems from the ground up for microscopy imaging tasks such as phase retrieval, requires substantial scientific expertise and creativity. To augment the trad…
cs.LG2026
InstructPro: Natural Language Guided Ligand-Binding Protein Design
Zhenqiao Song, Ramith Hettiarachchi, Chuan Li +2
The de novo design of ligand-binding proteins with tailored functions is essential for advancing biotechnology and molecular medicine, yet existing AI approaches are limited by sca…
cs.LG2025
OMTRA: A Multi-Task Generative Model for Structure-Based Drug Design
Ian Dunn, Liv Toft, Tyler Katz +4
Structure-based drug design (SBDD) focuses on designing small-molecule ligands that bind to specific protein pockets. Computational methods are integral in modern SBDD workflows an…