25 citations · 39 across the 5 of their papers we have counts for
6 papers
An intermediate phase in DNA melting
Richard A. Neher, Ulrich Gerland
We predict a novel temperature-driven phase transition of DNA below the melting transition. The additional, intermediate phase exists for repetitive sequences, when the two strands…
DNA as a programmable viscoelastic nanoelement
Richard A. Neher, Ulrich Gerland
The two strands of a DNA molecule with a repetitive sequence can pair into many different basepairing patterns. For perfectly periodic sequences, early bulk experiments of Poerschk…
Transcriptional Regulation by the Numbers 2: Applications
Lacramioara Bintu, Nicolas E. Buchler, Hernan G. Garcia +5
With the increasing amount of experimental data on gene expression and regulation, there is a growing need for quantitative models to describe the data and relate them to the diffe…
Transcriptional Regulation by the Numbers 1: Models
Lacramioara Bintu, Nicolas E. Buchler, Hernan G. Garcia +4
The study of gene regulation and expression is often discussed in quantitative terms. In particular, the expression of genes is regularly characterized with respect to how much, ho…
The style of genetic computing
Nicolas E. Buchler, Ulrich Gerland, Terence Hwa
Cells receive a wide variety of cellular and environmental signals, which must be processed combinatorially to generate specific and timely genetic responses. We present here a the…
On the Selection and Evolution of Regulatory DNA Motifs
Ulrich Gerland, Terence Hwa
The mutation and selection of regulatory DNA sequences is presented as an ideal model system of molecular evolution where genotype, phenotype, and fitness can be explicitly and ind…