282 citations · 2.1k across the 32 of their papers we have counts for
5 papers · 1 filter
Target search on a dynamic DNA molecule
Thomas Schötz, Richard A. Neher, Ulrich Gerland
We study a protein-DNA target search model with explicit DNA dynamics applicable to in vitro experiments. We show that the DNA dynamics plays a crucial role for the effectiveness o…
Optimal flexibility for conformational transitions in macromolecules
Richard A. Neher, Wolfram Mobius, Erwin Frey +1
Conformational transitions in macromolecular complexes often involve the reorientation of lever-like structures. Using a simple theoretical model, we show that the rate of such tra…
An intermediate phase in DNA melting
Richard A. Neher, Ulrich Gerland
We predict a novel temperature-driven phase transition of DNA below the melting transition. The additional, intermediate phase exists for repetitive sequences, when the two strands…
DNA as a programmable viscoelastic nanoelement
Richard A. Neher, Ulrich Gerland
The two strands of a DNA molecule with a repetitive sequence can pair into many different basepairing patterns. For perfectly periodic sequences, early bulk experiments of Poerschk…
Dynamics of force-induced DNA slippage
Richard A. Neher, Ulrich Gerland
We study the basepairing dynamics of DNA with repetitive sequences where local strand slippage can create, annihilate, and move bulge loops. Using an explicit theoretical model, we…