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19982025
most citedMultiscale polar theory of microtubule and motor-protein assemblies

148 citations · 773 across the 23 of their papers we have counts for

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Showing physics.bio-phShow all

12 papers · 1 filter

physics.bio-ph2020

Comparison of explicit and mean-field models of cytoskeletal filaments with crosslinking motors

Adam R. Lamson, Jeffrey M. Moore, Fang Fang +3

In cells, cytoskeletal filament networks are responsible for cell movement, growth, and division. Filaments in the cytoskeleton are driven and organized by crosslinking molecular m…

physics.bio-ph2017★ 13 cited

Effects of soft interactions and bound mobility on diffusion in crowded environments: a model of sticky and slippery obstacles

Michael W. Stefferson, Samantha A. Norris, Franck J. Vernerey +2

Crowded environments modify the diffusion of macromolecules, generally slowing their movement and inducing transient anomalous subdiffusion. The presence of obstacles also modifies…

physics.bio-ph2016★ 15 cited

Phase-plane analysis of the totally asymmetric simple exclusion process with binding kinetics and switching between antiparallel lanes

Hui-Shun Kuan, Meredith D. Betterton

Motor protein motion on biopolymers can be described by models related to the totally asymmetric simple exclusion process (TASEP). Inspired by experiments on the motion of kinesin-…

physics.bio-ph2015★ 29 cited

Motor protein accumulation on antiparallel microtubule overlaps

Hui-Shun Kuan, M. D. Betterton

Biopolymers serve as one-dimensional tracks on which motor proteins move to perform their biological roles. Motor protein phenomena have inspired theoretical models of one-dimensio…

physics.bio-ph2013★ 32 cited

Biophysics of filament length regulation by molecular motors

Hui-Shun Kuan, M. D. Betterton

Regulating physical size is an essential problem that biological organisms must solve from the subcellular to the organismal scales, but it is not well understood what physical pri…

physics.bio-ph2008★ 47 cited

Microtubule depolymerization by the kinesin-8 motor Kip3p: a mathematical model

L. E. Hough, Anne Schwabe, Matthew A. Glaser +2

Proteins from the kinesin-8 family promote microtubule (MT) depolymerization, a process thought to be important for the control of microtubule length in living cells. In addition t…