295 citations · 1.2k across the 41 of their papers we have counts for
4 papers · 1 filter
First passage times to T cell activation
Tony Wong, Ikchang Cho, Maria R. D'Orsogna +1
Effective recognition of foreign antigens by the adaptive immune system relies on T cells being activated by antigen-presenting cells (APCs) in lymph nodes. Here, diffusing T cells…
A probabilistic model of relapse in drug addiction
Sayun Mao, Tom Chou, Maria D'Orsogna
More than 60% of individuals recovering from substance use disorder relapse within one year. Some will resume drug consumption even after decades of abstinence. The cognitive and p…
Quantifying the Sensitivity of HIV-1 Viral Entry to Receptor and Coreceptor Expression
Bhaven Mistry, Maria R. D'Orsogna, Nicholas E. Webb +2
Infection by many viruses begins with fusion of viral and cellular lipid membranes, followed by entry of viral contents into the target cell and ultimately, after many biochemical…
The Effects of Statistical Multiplicity of Infection on Virus Quantification and Infectivity Assays
Bhaven Mistry, Maria R. D'Orsogna, Tom Chou
Many biological assays are employed in virology to quantify parameters of interest. Two such classes of assays, virus quantification assays (VQA) and infectivity assays (IA), aim t…