17 papers
Large language models improve physician accuracy but lead to false reliance
Tirtha Chanda, Christoph Wies, Franziska Schramm +10
Retrieval-augmented large language models (LLMs) promise source-linked clinical support, but their value depends on whether displayed evidence guides rather than distorts physician…
Foundation-model-guided radiogenomic discovery linking cancer genomes to cancer scans
Frederik Hauke, Jeremias Krause, Patrick Wienholt +6
The function of many genes is still unknown, and conventional driver-discovery methods, which rely on how frequently a gene is mutated, cannot assess genes that are only rarely aff…
Bayesian uncertainty estimation improves clinical decision making in medical AI agents
Frederik Hauke, Patrick Wienholt, Christiane Kuhl +4
Machine learning models for medical image analysis typically lack a reliable measure of confidence, limiting their use in ambiguous or atypical cases. Here we show that Monte Carlo…
Self-supervision drives representational convergence in medical foundation models more than clinical supervision
Soroosh Tayebi Arasteh, Sebastian Ziegelmayer, Mahshad Lotfinia +4
Medical image encoders from different groups are increasingly treated as interchangeable, on the assumption that scale and clinical supervision concentrate their representations on…
From Clinical Intent to Clinical Model: Autonomous Coding-Agents for Clinician-driven AI Development
Zihao Zhao, Frederik Hauke, Juliana De Castilhos +4
Developing AI models that are useful in clinical practice, requires efficient collaboration between clinicians and AI developers. This poses a practical challenge: clinicians must…
A European Multi-Center Breast Cancer MRI Dataset
Gustav Müller-Franzes, Lorena Escudero Sánchez, Nicholas Payne +18
Early detection of breast cancer is critical for improving patient outcomes. While mammography remains the primary screening modality, magnetic resonance imaging (MRI) is increasin…