6 papers
UNIStainNet: Foundation-Model-Guided Virtual Staining of H&E to IHC
Jillur Rahman Saurav, Thuong Le Hoai Pham, Pritam Mukherjee +3
Virtual immunohistochemistry (IHC) staining from hematoxylin and eosin (H&E) images can accelerate diagnostics by providing preliminary molecular insight directly from routine sect…
Cross-Domain Image Synthesis: Generating H&E from Multiplex Biomarker Imaging
Jillur Rahman Saurav, Mohammad Sadegh Nasr, Jacob M. Luber
While multiplex immunofluorescence (mIF) imaging provides deep, spatially-resolved molecular data, integrating this information with the morphological standard of Hematoxylin & Eos…
Dual Codebook VQ: Enhanced Image Reconstruction with Reduced Codebook Size
Parisa Boodaghi Malidarreh, Jillur Rahman Saurav, Thuong Le Hoai Pham +5
Vector Quantization (VQ) techniques face significant challenges in codebook utilization, limiting reconstruction fidelity in image modeling. We introduce a Dual Codebook mechanism…
Predicting Future States with Spatial Point Processes in Single Molecule Resolution Spatial Transcriptomics
Biraaj Rout, Priyanshi Borad, Parisa Boodaghi Malidarreh +6
In this paper, we introduce a pipeline based on XGboost to predict the future distribution of cells that are expressed by the Sog-D gene (active cells) in both the Anterior to post…
Peptide Sequencing Via Protein Language Models
Thuong Le Hoai Pham, Jillur Rahman Saurav, Aisosa A. Omere +9
We introduce a protein language model for determining the complete sequence of a peptide based on measurement of a limited set of amino acids. To date, protein sequencing relies on…
SpatialVisVR: An Immersive, Multiplexed Medical Image Viewer With Contextual Similar-Patient Search
Jai Prakash Veerla, Partha Sai Guttikonda, Amir Hajighasemi +7
In contemporary pathology, multiplexed immunofluorescence (mIF) and multiplex immunohistochemistry (mIHC) present both significant opportunities and challenges. These methodologies…