3 papers
physics.med-ph2026
Tau-induced atrophy drives functional connectivity disruption in Alzheimer's disease
Kun Jiang, Can Liao, Sujin Jiang +9
Alzheimer's disease involves progressive tau accumulation and spread, leading to regional brain atrophy and disruption of large-scale functional networks. While tau propagation and…
q-bio.NC2025
Neuron Platonic Intrinsic Representation From Dynamics Using Contrastive Learning
Wei Wu, Can Liao, Zizhen Deng +2
The Platonic Representation Hypothesis suggests a universal, modality-independent reality representation behind different data modalities. Inspired by this, we view each neuron as…
q-bio.QM2025
Molecule-dynamic-based Aging Clock and Aging Roadmap Forecast with Sundial
Wei Wu, Zizhen Deng, Chi Zhang +2
Addressing the unavoidable bias inherent in supervised aging clocks, we introduce Sundial, a novel framework that models molecular dynamics through a diffusion field, capturing bot…