2 papers
q-bio.QM2026
Empowering Chemical Structures with Biological Insights for Scalable Phenotypic Virtual Screening
Xiaoqing Lian, Pengsen Ma, Tengfeng Ma +9
Motivation: The scalable identification of bioactive compounds is essential for contemporary drug discovery. This process faces a key trade-off: structural screening offers scalabi…
cs.AI2024
TransMA: an explainable multi-modal deep learning model for predicting properties of ionizable lipid nanoparticles in mRNA delivery
Kun Wu, Zixu Wang, Xiulong Yang +4
As the primary mRNA delivery vehicles, ionizable lipid nanoparticles (LNPs) exhibit excellent safety, high transfection efficiency, and strong immune response induction. However, t…