19 citations · 58 across the 11 of their papers we have counts for
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q-bio.MN2008★ 6 cited
Sensitivity Regulation based on Noise Propagation in Stochastic Reaction Networks
Kyung Hyuk Kim, Hong Qian, Herbert M. Sauro
In this work we focus on how noise propagates in biochemical reaction networks and affects sensitivities of the system. We discover that the stochastic fluctuations can enhance sen…
q-bio.MN2007★ 19 cited
MAPK Cascades as Feedback Amplifiers
Herbert M Sauro, Brian Ingalls
Interconvertible enzyme cascades, exemplified by the mitogen activated protein kinase (MAPK) cascade, are a frequent mechanism in signal transduction pathways. There has been much…
q-bio.MN2005★ 16 cited
A p53 Oscillator Model of DNA Break Repair Control
Vijay Chickarmane, Ali Nadim, Animesh Ray +1
The transcription factor p53 is an important regulator of cell fate. Mutations in p53 gene are associated with many cancers. In response to signals such as DNA damage, p53 controls…