5 papers
CardioComposer: Leveraging Differentiable Geometry for Compositional Control of Anatomical Diffusion Models
Karim Kadry, Shoaib Goraya, Ajay Manicka +4
Generative models of 3D cardiovascular anatomy can synthesize informative structures for clinical research and medical device evaluation, but face a trade-off between geometric con…
Nano-engineered surface enhanced Raman spectroscopy substrates for probing tissue-material interactions
Connie M. Wang, Roberta M. Sabino, Aditya Garg +3
Innovation in biomaterials has brought both breakthroughs and new challenges in medicine, as implant materials have become increasingly multifunctional and complex. One of the grea…
Anatomica: Localized Control over Geometric and Topological Properties for Anatomical Diffusion Models
Karim Kadry, Abdallah Abdelwahed, Shoaib Goraya +4
We present Anatomica: an inference-time framework for generating multi-class anatomical voxel maps with localized geo-topological control. During generation, we use cuboidal contro…
The Dissipation Theory of Aging: A Quantitative Analysis Using a Cellular Aging Map
Farhan Khodaee, Rohola Zandie, Yufan Xia +1
We propose a new theory for aging based on dynamical systems and provide a data-driven computational method to quantify the changes at the cellular level. We use ergodic theory to…
Cellular Development Follows the Path of Minimum Action
Rohola Zandie, Farhan Khodaee, Yufan Xia +1
Cellular development follows a stochastic yet rule-governed trajectory, though the underlying principles remain elusive. Here, we propose that cellular development follows paths of…