2 papers
cs.AI2026
MUSS: A Multi-scale and Sequence-based Model for Single-cell Gene Regulation
Kangjie Zheng, Amirhossein Vahidi, Liying Jin +7
Modeling gene regulation in single cells requires jointly representing DNA sequence, chromatin accessibility, and gene expression across regulatory scales. Sequence-based models ca…
cs.LG2026
Locality-Controlled Out-of-Distribution Guidance for Robust Regulatory DNA Sequence Design
Dabin Jeong, Marwane Bourdim, Mo Lotfollahi
Designing regulatory DNA sequences for targeted gene-expression control is an important challenge. Recent approaches frame this task as property-conditioned generation, where diffu…