58 citations · 105 across the 4 of their papers we have counts for
4 papers
An innovative in silico model of the oral mucosa reveals the impact of extracellular spaces on chemical permeation through epithelium
Sean M. Edwards, Amy L. Harding, Joseph A. Leedale +4
In pharmaceutical therapeutic design or toxicology, accurately predicting the permeation of chemicals through human epithelial tissues is crucial, where permeation is significantly…
Gyrotactic swimmer dispersion in pipe flow: testing the theory
O. A. Croze, R. N. Bearon, M. A. Bees
Suspensions of microswimmers are a rich source of fascinating new fluid mechanics. Recently we predicted the active pipe flow dispersion of gyrotactic microalgae, whose orientation…
Modeling the dynamics of hypoxia inducible factor-1α (HIF-1α) within single cells and 3D cell culture systems
Joseph Leedale, Anne Herrmann, James Bagnall +4
HIF (Hypoxia Inducible Factor) is an oxygen-regulated transcription factor that mediates the intracellular response to hypoxia in human cells. There is increasing evidence that cel…
Biased swimming cells do not disperse in pipes as tracers: a population model based on microscale behaviour
R. N. Bearon, M. A. Bees, O. A. Croze
There is much current interest in modelling suspensions of algae and other micro-organisms for biotechnological exploitation, and many bioreactors are of tubular design. Using gene…