21 citations · 50 across the 9 of their papers we have counts for
9 papers
Sequence selection by dynamical symmetry breaking in an autocatalytic binary polymer model
Harold Fellermann, Shinpei Tanaka, Steen Rasmussen
Template directed replication of nucleic acids is at the essence of all living beings and a major milestone for any origin of life scenario. We here present an idealized model of p…
Non-Equilibrium Thermodynamics of Self-Replicating Protocells
Harold Fellermann, Bernat Corominas-Murtra, Per Lyngs Hansen +3
We provide a non-equilibrium thermodynamic description of the life-cycle of a droplet based, chemically feasible, system of protocells. By coupling the protocells metabolic kinetic…
Sequence selection in an autocatalytic binary polymer model
Shinpei Tanaka, Harold Fellermann, Steen Rasmussen
An autocatalytic pattern matching polymer system is studied as an abstract model for chemical ecosystem evolution. Highly ordered populations with particular sequence patterns appe…
Non-Ideality of a DNA Strand Displacement AND Gate Studied with a Dynamic Bonded DNA Model
Carsten Svaneborg, Harold Fellermann, Steen Rasmussen
We perform a spatially resolved simulation study of an AND gate based on DNA strand displacement using several lengths of the toehold and the adjacent domains. DNA strands are mode…
DNA Self-Assembly and Computation Studied with a Coarse-grained Dynamic Bonded Model
Carsten Svaneborg, Harold Fellermann, Steen Rasmussen
We study DNA self-assembly and DNA computation using a coarse-grained DNA model within the directional dynamic bonding framework {[}C. Svaneborg, Comp. Phys. Comm. 183, 1793 (2012)…
On the Growth Rate of Non-Enzymatic Molecular Replicators
Harold Fellermann, Steen Rasmussen
It is well known that non-enzymatic template directed molecular replicators X + nO ---> 2X exhibit parabolic growth d[X]/dt = k [X]^{1/2}. Here, we analyze the dependence of the ef…