5 papers
Efficient Variance Estimation for the Polytomous Discrimination Index
Qunqiang Feng, Taozheng Jia, Pan Liu +2
Evaluating diagnostic accuracy for multi-category outcomes remains a significant challenge, primarily due to computational limitations in existing performance metrics. The Polytomo…
Value-of-Information Analysis for External Validation of Risk Prediction Models in Multicenter Studies and Systematic Reviews
Laure Wynants, Kim Zhipei Wang, Sabine Grimm +5
External validation studies have finite sample sizes, creating uncertainty about whether a prediction model's Net Benefit (NB) exceeds default strategies' NB. The expected value of…
The fundamental problem of risk prediction for individuals: health AI, uncertainty, and personalized medicine
Lasai Barreñada, Ewout W Steyerberg, Dirk Timmerman +3
Background and Objective: Clinical prediction models are commonly evaluated regarding performance for a population, although decisions are made for individuals. The classic view re…
Critical Appraisal of Fairness Metrics in Clinical Predictive AI
João Matos, Ben Van Calster, Leo Anthony Celi +6
Predictive artificial intelligence (AI) offers an opportunity to improve clinical practice and patient outcomes, but risks perpetuating biases if fairness is inadequately addressed…
Challenges and recommendations for Electronic Health Records data extraction and preparation for dynamic prediction modelling in hospitalized patients -- a practical guide
Elena Albu, Shan Gao, Pieter Stijnen +6
Dynamic predictive modelling using electronic health record (EHR) data has gained significant attention in recent years. The reliability and trustworthiness of such models depend h…