2 papers
stat.ME2026
Prediction intervals for overdispersed multinomial data with application to historical controls
Sören Budig, Frank Schaarschmidt, Max Menssen
In pharmaceutical and toxicological research, historical control data are increasingly used to validate concurrent control groups, typically via the construction of historical cont…
stat.ME2026
Including historical control data in simultaneous inference for pre-clinical multi-arm studies
Max Menssen, Carsten Kneuer, Gyamfi Akyianu +3
In pre- and non-clinical toxicology, the reduction of animal use is highly desireable. Although approaches for possible sample size reduction in the concurrent control group were s…