3 papers
q-bio.PE2026
Sex chromosome stability and turnover across vertebrates: a developmental gene regulatory network perspective
Wen-Juan Ma, Ricard Fontserè, Tristan Cornelis +2
Sex chromosomes have evolved repeatedly across the Tree of Life, yet their evolutionary fates differ strikingly. In sharp contrast to mammals and birds with degenerated, stable Y/W…
q-bio.QM2025
Decoding Dmrt1: Insights into vertebrate sex determination and gonadal sex differentiation
Barbora Augstenová, Wen-Juan Ma
Dmrt1 is pivotal in testis formation and function by interacting with genes crucial for Sertoli cell differentiation. Dmrt1, or Sox9, forms a conserved antagonistic interaction wit…
q-bio.PE2024
Sex chromosome evolution: The classical paradigm and so much beyond
Paris Veltsos, Sagar Shinde, Wen-Juan Ma
Sex chromosomes have independently evolved in species with separate sexes in most lineages across the tree of life. However, the well-accepted canonical model of sex chromosome evo…