most citedA two-state kinetic model for the unfolding of single molecules by mechanical force

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physics.bio-ph2002★ 120 cited

A two-state kinetic model for the unfolding of single molecules by mechanical force

F. Ritort, C. Bustamante, I. Tinoco

We investigate the work dissipated during the irreversible unfolding of single molecules by mechanical force, using the simplest model necessary to represent experimental data. The…