30 citations · 42 across the 3 of their papers we have counts for
3 papers
Protein-mediated DNA Loop Formation and Breakdown in a Fluctuating Environment
Yih-Fan Chen, J. N. Milstein, Jens-Christian Meiners
Living cells provide a fluctuating, out-of-equilibrium environment in which genes must coordinate cellular function. DNA looping, which is a common means of regulating transcriptio…
Femtonewton Forces Can Control Protein-Meditated DNA Looping
Yih-Fan Chen, J. N. Milstein, J. -C. Meiners
We show that minuscule entropic forces, on the order of 100 fN, can prevent the formation of DNA loops--a ubiquitous means of regulating the expression of genes. We observe a tenfo…
A Generalized Theory of DNA Looping and Cyclization
David P. Wilson, Alexei V. Tkachenko, Jens-Christian Meiners
We have developed a generalized semi-analytic approach for efficiently computing cyclization and looping factors of DNA under arbitrary binding constraints. Many biological sys…