2 papers
stat.ME2026
On the inclusion of non-concurrent controls in platform trials with an interim analysis
Pavla Krotka, Martin Posch, Marta Bofill Roig
The analysis of platform trials can be enhanced by utilizing non-concurrent controls. Since including this data might also introduce bias in the treatment effect estimators if time…
stat.ME2025
Statistical modeling to adjust for time trends in adaptive platform trials utilizing non-concurrent controls
Pavla Krotka, Martin Posch, Mohamed Gewily +2
Utilizing non-concurrent control data (NCC) in the analysis of late-entering arms in platform trials has recently received considerable attention. While incorporating NCC can lead…