3 papers
q-bio.QM2010
Graphical models for inferring single molecule dynamics
Jonathan E. Bronson, Jake M. Hofman, Jingyi Fei +2
Background: The recent explosion of experimental techniques in single molecule biophysics has generated a variety of novel time series data requiring equally novel computational to…
q-bio.BM2009
Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation
Jingyi Fei, Jonathan E. Bronson, Jake M. Hofman +3
Determining the mechanism by which transfer RNAs (tRNAs) rapidly and precisely transit through the ribosomal A, P and E sites during translation remains a major goal in the study o…
q-bio.QM2009
Learning Rates and States from Biophysical Time Series: A Bayesian Approach to Model Selection and Single-Molecule FRET Data
Jonathan E. Bronson, Jingyi Fei, Jake M. Hofman +2
Time series data provided by single-molecule Forster resonance energy transfer (sm-FRET) experiments offer the opportunity to infer not only model parameters describing molecular c…