61 citations · 102 across the 3 of their papers we have counts for
4 papers
Bone refilling in cortical bone multicellular units: Insights into tetracycline double labelling from a computational model
Pascal R. Buenzli, Peter Pivonka, David W. Smith
Bone remodelling is carried out by `bone multicellular units' (BMUs) in which active osteoclasts and active osteoblasts are spatially and temporally coupled. The refilling of new b…
Mechanobiological regulation of bone remodeling -- Theoretical development of a coupled systems biology-micromechanical approach
Stefan Scheiner, Peter Pivonka, Christian Hellmich +1
Bone remodeling involves the coordinated removal of bone by osteoclasts and addition of bone by osteoblasts, a process that is modulated by the prevailing mechanical environment. I…
Modelling the anabolic response of bone using a cell population model
Pascal R. Buenzli, Peter Pivonka, Bruce S. Gardiner +1
To maintain bone mass during bone remodelling, coupling is required between bone resorption and bone formation. This coordination is achieved by a network of autocrine and paracrin…
Investigation of bone resorption within a cortical basic multicellular unit using a lattice-based computational model
P. R. Buenzli, J. Jeon, P. Pivonka +2
In this paper we develop a lattice-based computational model focused on bone resorption by osteoclasts in a single cortical basic multicellular unit (BMU). Our model takes into acc…