most citedThe Influence of Spatial Variation in Chromatin Density Determined by X-ray Tomograms on the Time to Find DNA Binding Sites

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q-bio.SC2013★ 18 cited

The Influence of Spatial Variation in Chromatin Density Determined by X-ray Tomograms on the Time to Find DNA Binding Sites

Samuel A. Isaacson, Carolyn A. Larabell, Mark A. Le Gros +2

In this work we examine how volume exclusion caused by regions of high chromatin density might influence the time required for proteins to find specific DNA binding sites. The spat…