2 papers
q-bio.CB2013
Self tolerance in a minimal model of the idiotypic network
Robert Schulz, Benjamin Werner, Ulrich Behn
We consider the problem of self tolerance in the frame of a minimalistic model of the idiotypic network. A node of this network represents a population of B lymphocytes of the same…
q-bio.PE2013
A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissues
B. Werner, D. Dingli, A. Traulsen
We model a general, hierarchically organized tissue by a multi compartment approach, allowing any number of mutations within a cell. We derive closed solutions for the deterministi…