24 citations · 34 across the 3 of their papers we have counts for
3 papers
q-bio.GN2013
Can we predict the mutation rate at the single nucleotide scale in the human genome?
Adam Eyre-Walker, Ying Chen
It has been recently claimed that it is possible to predict the rate of de novo mutation of each site in the human genome with almost perfect accuracy (Michaelson et al. (2012) Cel…
q-bio.PE2013★ 10 cited
The role of mutation rate variation and genetic diversity in the architecture of human disease
Ying Chen Eyre-Walker, Adam Eyre-Walker
We have investigated the role that the mutation rate and the structure of genetic variation at a locus play in determining whether a gene is involved in disease. We predict that th…
q-bio.PE2013★ 24 cited
Fluctuating selection models and McDonald-Kreitman type analyses
Toni I. Gossmann, David Waxman, Adam Eyre-Walker
It is likely that the strength of selection acting upon a mutation varies through time due to changes in the environment. However, most population genetic theory assumes that the s…