9 citations · 23 across the 4 of their papers we have counts for
4 papers
Minimizing Metastatic Risk in Radiotherapy Fractionation Schedules
Hamidreza Badri, Jagdish Ramakrishnan, Kevin Leder
Metastasis is the process by which cells from a primary tumor disperse and form new tumors at distant anatomical locations. The treatment and prevention of metastatic cancer remain…
Optimization of Radiation Therapy Fractionation Schedules in the Presence of Tumor Repopulation
Thomas Bortfeld, Jagdish Ramakrishnan, John N. Tsitsiklis +1
We analyze the effect of tumor repopulation on optimal dose delivery in radiation therapy. We are primarily motivated by accelerated tumor repopulation towards the end of radiation…
Exploiting tumor shrinkage through temporal optimization of radiotherapy
Jan Unkelbach, David Craft, Theodore Hong +5
In multi-stage radiotherapy, a patient is treated in several stages separated by weeks or months. This regimen has been motivated mostly by radiobiological considerations, but also…
A Dynamic Programming Approach to Adaptive Fractionation
Jagdish Ramakrishnan, David Craft, Thomas Bortfeld +1
We conduct a theoretical study of various solution methods for the adaptive fractionation problem. The two messages of this paper are: (i) dynamic programming (DP) is a useful fram…