Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity

Margaret M. Stratton, Il-Hyung Lee, Moitrayee Bhattacharyya +5

The activation of the dodecameric Ca2+/calmodulin dependent kinase II (CaMKII) holoenzyme is critical for the formation of memory. We now report that CaMKII has a remarkable proper…