10 papers
Evidence-based diagnostic reasoning with multi-agent copilot for human pathology
Luca L. Weishaupt, Chengkuan Chen, Drew F. K. Williamson +8
Pathology is experiencing rapid digital transformation driven by whole-slide imaging and artificial intelligence (AI). While deep learning-based computational pathology has achieve…
Towards Spatial Transcriptomics-driven Pathology Foundation Models
Konstantin Hemker, Andrew H. Song, Cristina Almagro-Pérez +6
Spatial transcriptomics (ST) provides spatially resolved measurements of gene expression, enabling characterization of the molecular landscape of human tissue beyond histological a…
NOVA: An Agentic Framework for Automated Histopathology Analysis and Discovery
Anurag J. Vaidya, Felix Meissen, Daniel C. Castro +7
Digitized histopathology analysis involves complex, time-intensive workflows and specialized expertise, limiting its accessibility. We introduce NOVA, an agentic framework that tra…
MEDEQUALQA: Evaluating Biases in LLMs with Counterfactual Reasoning
Rajarshi Ghosh, Abhay Gupta, Hudson McBride +2
Large language models (LLMs) are increasingly deployed in clinical decision support, yet subtle demographic cues can influence their reasoning. Prior work has documented disparitie…
A Foundation Model for Spatial Proteomics
Muhammad Shaban, Yuzhou Chang, Huaying Qiu +57
Foundation models have begun to transform image analysis by acting as pretrained generalist backbones that can be adapted to many tasks even when post-training data are limited, ye…
Composable Interventions for Language Models
Arinbjorn Kolbeinsson, Kyle O'Brien, Tianjin Huang +8
Test-time interventions for language models can enhance factual accuracy, mitigate harmful outputs, and improve model efficiency without costly retraining. But despite a flood of n…