8 papers
Evidence-based diagnostic reasoning with multi-agent copilot for human pathology
Luca L. Weishaupt, Chengkuan Chen, Drew F. K. Williamson +8
Pathology is experiencing rapid digital transformation driven by whole-slide imaging and artificial intelligence (AI). While deep learning-based computational pathology has achieve…
NOVA: An Agentic Framework for Automated Histopathology Analysis and Discovery
Anurag J. Vaidya, Felix Meissen, Daniel C. Castro +7
Digitized histopathology analysis involves complex, time-intensive workflows and specialized expertise, limiting its accessibility. We introduce NOVA, an agentic framework that tra…
AI-driven 3D Spatial Transcriptomics
Cristina Almagro-Pérez, Andrew H. Song, Luca Weishaupt +13
A comprehensive three-dimensional (3D) map of tissue architecture and gene expression is crucial for illuminating the complexity and heterogeneity of tissues across diverse biomedi…
Multimodal Whole Slide Foundation Model for Pathology
Tong Ding, Sophia J. Wagner, Andrew H. Song +20
The field of computational pathology has been transformed with recent advances in foundation models that encode histopathology region-of-interests (ROIs) into versatile and transfe…
HEST-1k: A Dataset for Spatial Transcriptomics and Histology Image Analysis
Guillaume Jaume, Paul Doucet, Andrew H. Song +8
Spatial transcriptomics enables interrogating the molecular composition of tissue with ever-increasing resolution and sensitivity. However, costs, rapidly evolving technology, and…
Morphological Prototyping for Unsupervised Slide Representation Learning in Computational Pathology
Andrew H. Song, Richard J. Chen, Tong Ding +3
Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide represent…