355 citations · 355 across the 3 of their papers we have counts for
3 papers
No evidence that natural selection has been less effective at removing deleterious mutations in Europeans than in West Africans
Ron Do, Daniel Balick, Heng Li +3
Non-African populations have experienced major bottlenecks in the time since their split from West Africans, which has led to the hypothesis that natural selection to remove weakly…
Response to a population bottleneck can be used to infer recessive selection
Daniel J. Balick, Ron Do, David Reich +1
Here we present the first genome wide statistical test for recessive selection. This test uses explicitly non-equilibrium demographic differences between populations to infer the m…
The impact of deleterious passenger mutations on cancer progression
Christopher D McFarland, Gregory V Kryukov, Shamil Sunyaev +1
Cancer progression is driven by a small number of genetic alterations accumulating in a neoplasm. These few driver alterations reside in a cancer genome alongside tens of thousands…